Redesigned hip joints need a simulator

People are living longer than ever. But a long life has its price. With age come more diseases and health issues, such as hip problems that can limit a person’s mobility. 

Hip replacement procedures have become common, although implants have a lifespan too. It might happen that a hip replacement you get at 60 needs to be replaced at 75. This is not the ideal scenario.

To minimise these cases, researchers are testing new materials and designs to prolong prostheses’ lifespans. These potential solutions need to be tested, but each test costs tens of thousands of euro. Enter, the University of Malta’s hip joint simulator.

Hip joint simulator in all its glory.

The hip joint simulator is a machine that replicates the joint movements and loads imposed on the human hip. To do so, the simulator uses three stainless steel frames, each of which can be controlled independently using motors. These motors act as the ‘muscles’ of the hip, programmed to replicate the walking cycle during testing.

When it comes to simulating load and forces, a mechanism can load the implants with weights of up to 300kg in a fraction of a second. This emulates what happens while walking, when the weight of the body rests on one leg due to the body’s shift in the centre of gravity. While running, inertial forces can cause the hip to sometimes take five times a person’s body weight.

Finally, to simulate the environment inside the human body, researchers use a specialised solution that mimics the bodily fluids surrounding the hip joint. They even warm the fluid to imitate body temperature. 

The hip joint simulator forms part of the MaltaHip project that intends to radically redesign hip implants to give them the longer lifespan patients want and need. Watch this space for more.  

The MALTAHIP project is funded by the Malta Council for Science and Technology through FUSION: The R&I Technology Development Programme 2016 (R&I-2015-023T).

Research to business plan: A metamorphosis

Author: Michelle Cortis

Michelle Cortis

In recent years, there has been a shift in the relationship between research and commercial industries. Commercial viability almost always comes into question for ongoing research. Commercialisation can be a boon. When a research project has demonstrated its potential to become a viable business, funding opportunities increase, meaning the research can be turned into a product or service that people can use.

In 2018, as part of a Masters in Knowledge-Based Entrepreneurship, I analysed the commercial potential of an ongoing University of Malta project. I conducted an in-depth market feasibility study on Prof. Ing Joseph Cilia’s Smart Micro Combined Heat and Power System, a device that can be fitted into homes and offices to deliver heat as a by-product of electricity, reducing energy costs. Many EU countries are setting up incentives to make these systems more feasible and attractive to consumers. 

For my dissertation, I developed a business plan for the research team. An engineer myself, and having earned a Masters by Research back in 2014, this was different to anything I had done before. My supervisors, Prof. Russell Smith and Dr Ing. Nicholas Sammut, helped me find the right balance between utilising my technical knowledge whilst also analysing the product’s commercial potential. Even my language changed through the process; I began to speak of ‘euros per day’ rather than ‘kilowatt hours’. I learnt to differentiate between technological features and what real benefits future users would gain.

Being presented with a physical product, initially one may assume that it is to be sold to customers, or protected through a patent and licensed to the private sector. However, my market analysis revealed new target audiences that had not been thought of before. Selling the device was not the only way to exploit the project’s commercial potential. What if we leased the product instead of selling it? Should we continue developing the product or is it already innovative enough? What if we developed a spin-out—would it be too expensive or is it worth the investment?  

By analysing a project through a commercial lens, all these questions arise, pointing out potential ways to make a good project great. But what makes a good business plan great is when all these questions are answered. 

The Project ‘A Smart Micro Combined Heat and Power System’ is financed by the Malta Council for Science & Technology, for and on behalf of the Foundation for Science and Technology through the FUSION: R&I Technology and Development Programme. 

Are you carrying out research at the University of Malta which you think may have commercial potential? If so, contact the Knowledge Transfer Office on knowledgetransfer@um.edu.mt

Of robots and rights

Author: Dr Jackie Mallia

Dr Jackie Mallia

In 2019, Malta will create a National Strategy for Artificial Intelligence or ‘AI’, in order to establish the Country as a hub for investment in AI. Speaking about AI at the Delta Summit late last year, Prime Minister Dr Joseph Muscat stated that ‘not only can we not stop change, but we have to embrace it with anticipation since it provides society with huge opportunities.’ He followed up with similar declarations at the Malta Innovation Summit, also observing that in the future ‘we may reach a stage where robots may be given rights under the law.’ 

This latter statement seemed to generate unease. Reading some of the negative comments posted online, I realised that for many, the mention of ‘AI’ still conjures up images of the Terminator movies. 

Although a machine possessing self-awareness, sentience, and consciousness may take decades to materialise, AI is already pervasive in our lives. Many of us make use of intelligent assistants, be it Amazon’s Alexa or Apple’s Siri. Others use Google Nest to adjust their home’s temperature. Then there are the millions with Netflix accounts whose content is ranked in order of assumed preference. All of it is convenient and all of it is due to AI. But some of the skepticism towards the technology may be warranted. High-profile failures include Google Home Minis allegedly sending their owners’ secretly recorded audio to Google. Facebook’s chatbots, Alice and Bob, developed their own language to conduct private conversations, leading to their shutdown. In addition, there were two well-documented fatal autonomous car accidents in 2018.

AI is still evolving, but at the same time, it is becoming ubiquitous, which leads us to some very important questions. What is happening to the data that such systems are collecting about us? What decisions are the devices taking, and to what extent are we even aware of them? Do we have a right to know the basis upon which such decisions are taken? If a machine’s ‘intelligence’ is based on big data being fed to it in an automated manner, how do we ensure it remains free from bias? Can decisions taken by a machine be explained in a court of law? Who is liable? 

A focus on the regulation of AI is not misplaced. The issues are real and present. But the answer is not to turn away from innovation. Progress will happen whether we want it to or not. Yes, we need ‘to embrace it,’ as Muscat stated, but we must do so in the most responsible way possible through appropriate strategy and optimal legislation.   

Dr Jackie Mallia is a lawyer specialising in Artificial Intelligence and a member of the Government of Malta’s AI Taskforce

What’s lurking on your lunch?

In our modern, fast-paced lives, more of us are turning to convenient ready-to-eat meals. But with short shelf lives and high demand, food safety tests just aren’t quick enough anymore. Dr Sholeem Griffin tells Becky Catrin Jones how an innovative collaboration between microbiology and computing is tackling this challenge.

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Finding the soul in the machine

Swiss artist, documentary filmmaker, and researcher Dr Adnan Hadzi has recently made Malta his home and can currently be found lecturing in interactive art at the University of Malta. He speaks to Teodor Reljic about how the information technology zeitgeist is spewing up some alarming developments, arguing that art may be our most appropriate bulwark against the onslaught of privacy invasion and the unsavoury aspects of artificial intelligence.

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Blood in the brain

Artificial intelligence (AI) has now made its way into the medical world. But it’s not as scary as it sounds. Most forms of AI are simply programs which have been developed to carry out very specific tasks–and they do them very well.

As part of my final-year project, I used AI to develop a program that can diagnose different types of brain haemorrhages. Brain haemorrhages are life-or-death situations where blood vessels in the brain burst and bleed into surrounding tissues, killing brain cells. Speed is key in preventing long-term brain damage, but treatment options depend on the size and location of the haemorrhage. This is when computerised tomography, or CT scans, come in.

Using X-rays, CT scans can image the brain in seconds. Last year, John Napier (another final-year project student) created an AI system to detect brain haemorrhages from CT scans. Building on this, I (under the supervision of Prof. Ing. Carl James Debono, Dr Paul Bezzina, and Dr Francis Zarb) developed a system to take the output from Napier’s system and further analyse the intensity, shape, and texture of haemorrhages to identify them as one of three types.

Kirsty Sant

The AI was trained on 24 pre-classified CT scans. By presenting the scan image to the artificial neural network along with the answer, the system can take on the information and learn. This process trains it to become familiar with the types of haemorrhage. Two different structures of artificial neural network were used with 220 variants each–resulting in 440 variants being used to train and test the model.

Then it was time to test this system. Six scans were given as unknowns and the network successfully classified over 88% of the haemorrhages using only three of the 440 variants.

The purpose of this system is to verify radiologists’ diagnoses. However, we hope to develop it to diagnose haemorrhages, which would help treat patients faster. The system can be adapted to other illnesses–CT scans are commonly used to image the abdomen and chest. The applications, and life-saving potential, are endless.

This research was carried out as part of a Bachelor’s degree in Computer Engineering at the Faculty of ICT, University of Malta.

Author: Kirsty Sant 

Underwater Eyes

Water covers 70% of Earth’s surface, but our oceans and seas might as well be alien planets. According to estimates, we’ve only explored about 5% of them so far. Crazy depths and dangerous conditions prevent humans from venturing into the unknown simply because we would be unable to survive. However, these limitations are being overcome. Drone technology can safely explore what lurks beneath the waves, and the Physical Oceanography Research Group from the Department of Geosciences at the University of Malta (UM) are doing just that.

Enter Powervision’s PowerRay Underwater Drone, an intelligent robot. It can capture real-time, high-res images beneath the sea’s surface. It has a wide-angle lens and instrumentation capable of determining temperature, sea depth, and even the presence of fish. Coupled with image processing and machine learning techniques being developed by the group, the drone maps the sea floor, determining its make-up as well as identifying locations where different fish species originate.
The small, lightweight drone can travel up to 1.5m/s and is currently being tested off the coast of Malta near Buġibba. This area has already been mapped manually by divers, which means that, when ready, the drone and human maps can be compared to evaluate the drone’s performance. If the AI algorithm produces accurate results, it will be used to charter unmapped regions—a first from Malta.

PowerRay Underwater Drone exploring the depths

But its applications don’t end there. The drone can also be used to monitor the condition of other expensive marine instruments which spend a lot of time underwater. Without having to put on a diving suit, it allows the team to check on deployed water temperature sensors, tide gauges, and acoustic Doppler current profilers. This helps to optimise and plan maintenance, which in turn prolongs the hardware’s lifetime.

The UM team also want to use the technology to detect marine litter. They plan to identify litter ‘hotspots’ in order to raise awareness and organise clean-up campaigns—a valuable initiative to support vital efforts to clean up our oceans.

  Author: Kirsty Callan

Accidental science

Do scientists need to have a clear end-goal before they dive down the research rabbit hole? Sara Cameron speaks to Dr André Xuereb about the winding journey that led to the unintended discovery of a new way to detect earthquakes.

Some of science’s greatest accomplishments were achieved when no one was looking with a purpose. When studying a petri dish of bacterial cultures, Alexander Fleming had no intention of discovering penicillin, and yet he changed the course of human history. Henri Becquerel was trying to make the most of dwindling sunlight to expose photographic plates using uranium when he stumbled upon radioactivity. A chance encounter between a chocolate bar in Percy Spencer’s pocket and the radar machine that melted it sparked the invention of the household microwave.

One would think that with this track record of coincidental breakthroughs, the field of science and research would continue to flourish by embracing curiosity and experimentation. But as interest piques and funding avenues pop up for researchers, there has been a shift in mindset.

Dr André Xuereb

Money changes things. And while it does allow people to work hard and answer more questions, it has also fostered expectations from stakeholders. Investors want fast results that will improve their business or product. We, the end-user, want to see our lives changed, one discovery at a ti me. We’re no longer satisfied with research for research’s sake. At least for the most part.

Quantum physicist Dr André Xuereb (Faculty of Science, University of Malta) is all too aware of this issue and its effects on scientific progress. Xuereb explains scientists’ frustration: ‘A lot of funding, in Malta and elsewhere, is dedicated to bringing mature ideas to the market, but that is the ti p of the iceberg. There is an entire innovation lifecycle that must be funded and sustained for good ideas to develop and eventually become technologies. The starting point is often an outlandish idea, and eventually, sometimes by accident, great new technologies are born,’ he says.

  STARTING POINTS

Over the past few years, Xuereb has been exploring new possibilities in quantum mechanics.

The field of quantum mechanics attempts to explain the behaviour of atoms and what makes them. Its mathematical principles show that atoms and other particles can exist in states beyond what can be described by the physics of the ordinary objects that surround us. For example, quantum theorems that show objects existing in two places at once off er a scientific basis for teleportation.

Star Trek fans know exactly what we’re talking about, but for those rolling their eyes, the reality is that many things in our everyday lives wouldn’t exist without at least some understanding of quantum physics. Our computers, phones, GPS navigation, digital cameras, LED TV screens, and lasers are all products of the quantum revolution.

The starting point is often an outlandish idea, and eventually, sometimes by accident,
great new technologies are born

Another technology that has changed the way we live and work is modern telecommunications technology. When you pick up your phone to message a friend overseas, call a loved one, or email a colleague, telecoms networks spanning the earth carry the data across continents and under oceans through thousands of kilometres of optical fibres.

The 96-kilometre submarine telecommunication link between Malta and Sicily was Xuereb’s focus in 2015. He organised a team of European experts to begin investigating the potential for building a quantum link between the two countries.

The Austrian, Italian, and Maltese trio were particularly interested in a strange property called ‘entanglement.’ This is a curious property of quantum objects that can be created in pairs of photons, connecting them together. This entanglement can be distributed by giving one of these photons to a friend and keeping the other for yourself, establishing a quantum link between you and this friend—an invisible quantum ‘wire,’ so to speak.

Through this connection, you and your friend can send data faster than over ordinary connections; by modifying the state of the photon at your end, you can instantly affect the state of your friend’s photon, no matter how far apart you are in the universe. Using quantum links such as these, all manner of feats can be performed, including super-secure communications. ‘We wanted to demonstrate that quantum entanglement can be distributed using a 100km-long, established telecoms link, using what was already available, with no laboratory facilities in sight,’ explains Xuereb. His team also wanted to demonstrate that entanglement using polarisation of light was possible. Previously it was thought impossible in submarine conditions, even though it has some very technologically convenient properties.

Two years and several complex experiments later, Xuereb and his team have indeed proven the possibility of quantum communications over submarine telecommunication networks. And with one question answered, a slew more lifted their heads.

The Italian subteam, led by Davide Calonico (Istituto Nazionale di Ricerca Metrologica, INRIM), now turned their attention to a different set of questions for the Malta-Sicily telecommunication network.

  MORE TO COME…

Atomic clocks keep the world ticking by providing precise timekeeping for GPS navigation, internet synchronisation, banking transactions, and particle science experiments. In all these activities, exact timing is essential.

These extremely accurate clocks use atomic oscillations as a frequency reference, giving them an average error of only one second every 100 million years. Connecting the world’s atomic clocks would create an international common time base, which would allow people to better synchronise their activities, even over vast distances. For example, bank transactions and trading could happen much faster than they do at present.

This can’t be done by bouncing signals off of spaceborne satellites, since tiny changes in the atmosphere or in satellite orbits can ruin the signal. This is where the fibre-optic network comes back into the picture. Researchers have recently been looking at the telecoms network as a way to make this synchronisation possible. Scientists can use an ultra-stable laser to shine a reference beam along these fibres. Monitoring the optical path and the phase of the optical signal of the beam can then allow them to compare and synchronise the clocks at both ends.

Whilst Calonico and his team were testing this idea on the submarine network between Malta and Sicily, a few thousand kilometres away, meteorology expert Dr Giuseppe Marra was monitoring an 80km link in England. On October 2016, everything changed. One night, he noticed some noise in his data. Unable to attribute the noise to misbehaving equipment or a monitoring malfunction, his gut told him to turn to the news from his home country, Italy. There, he saw that the town of Amatrice had been devastated by an earthquake of 5.9 magnitude.

Further testing confirmed that the waveforms Marra saw in the fibre data matched those recorded by the British Geological Survey during the earthquake. His system even recorded quakes as far away as New Zealand, Mexico and Japan. This was huge news.

Diagram illustrating how even the smallest underwater seismic waves can be detected.

In simple terms, the seismic waves from an earthquake tremor cause a series of very slight expansions and contractions in fibre-optic cables, which in turn modify the phase of the cable’s reference beam. These tiny disturbances can be captured by specialised measurement tools at the ends of the cable, capable of detecting changes on the scale of femtoseconds: a millionth of a billionth of a second.

The majority of seismometers are land-based and so small that earthquakes more than a few hundred kilometres from the coast go undetected. Conventional seismometers designed to monitor the seabed are expensive and don’t usually monitor underwater seismic activity in real time. Telecoms networks could offer a solution that would allow us to observe and understand seismic activity in the world’s vast oceans. They would open up a new window through which to observe the processes taking place underneath Earth’s surface, teaching us more about how our planet works. In future, it may even make it possible to detect large earthquakes that cause untold devastation earlier.

The beauty of this discovery is that the infrastructure already exists. No new work is needed. All that is required is to set up lasers at either end of these cables, using up a tiny portion of a cable’s bandwidth without interfering with its use.

  THREADS COMING TOGETHER

Marra got together with Xuereb and Calonico, who were already working on the undersea network between Malta and Sicily, to conduct some initial tests. The underwater trial, published in the world-leading journal Science this year along with the terrestrial results, was able to detect a weak tremor of 3.4 magnitude off Malta’s coast. Its epicentre was 89km from the cable’s nearest point, which reinforced the idea that cables can be used as a global seismic detector. ‘We would be able to monitor in real time tiny vibrations all over the planet. This would turn the existing network into a microphone for the Earth,’ Xuereb explains.

If we don’t fund the initial few steps of the innovation lifecycle,
how will we ever develop new technologies?

The system hasn’t been tested on an ocean cable. An interesting target would be a cable that crosses the mid-Atlantic ridge, where the drifting of Eurasian and African tectonic plates creates an area of high seismic activity. Based on the results so far and on conservative assumptions, trials are being planned for the near future on a larger scale, which will give us a better idea of the possibilities.

  FURTHER DOWN THE RABBIT HOLE…

In many ways, it is understandable that agencies that fund science favour smaller, more goal-driven research programmes. They seek tangible results in a timely manner to reap quick rewards. But as this story goes to show, a change in mentality is needed.

‘If we don’t fund the initial few steps of the innovation lifecycle, how will we ever develop new technologies? This is a problem that affects scientists from many countries and comes from a mismatch in timescales. A year is a long time in politics, but a decade is often a short time in science,’ Xuereb comments.

Innovation has to start from somewhere, and it often starts from ideas which may have no apparent relevance to our everyday lives. We need to support researchers by keeping an open mind to unknown long-term possibilities—or the world might not only miss the next earthquake but also the next life-changing discovery.

Author: Sara Cameron

Sewage works

Water is our number one resource. It not only sustains life, but also supports the economy and its development. And yet, water is taken for granted. Kirsty Callan talks to Marco Cremona, the man behind the revolutionary water treatment solution that promised to reduce Maltese hotels’ water use by 85%.

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